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Lung transplantation for bronchiolitis obliterans syndrome after allogenic hematopoietic stem cell transplantation

Fei Gao, Jingyu Chen, Dong Wei, Bo Wu, Min Zhou

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 224-228 doi: 10.1007/s11684-017-0538-3

Abstract:

Bronchiolitis obliterans syndrome (BOS) after hematopoietic stem cell transplantation (HSCT) is aLung transplantation (LTX) has been rarely reported as a treatment option for selected HSCT recipients

Keywords： bronchiolitis obliterans syndrome (BOS)     hematopoietic stem cell transplantation (HSCT)     lung transplantation    

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Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneicperipheral stem cell transplantation for adult patients with lymphoid malignancies: a prospective single-arm

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 108-115 doi: 10.1007/s11684-019-0730-8

Abstract: Post-transplantation cyclophosphamide (PT-Cy) alone or in combination with other immunosuppressive drugshas emerged as a promising strategy in the setting of allogeneic hematopoietic stem cell transplantationcyclosporine as graft-versus-host disease (GVHD) prophylaxis after myeloablative conditioning and T cell-repleteperipheral stem cell transplantation in lymphoid malignancies.

Keywords： post-transplantation cyclophosphamide     allogeneic hematopoietic stem cell transplantation     lymphoid malignancies    

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Risk stratification system for skin and soft tissue infections after allogeneic hematopoietic stem celltransplantation: PAH risk score

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 957-968 doi: 10.1007/s11684-021-0910-1

Abstract: However, to date, the profiles and clinical outcomes of SSTIs in hematopoietic stem cell transplantation

Keywords： skin and soft tissue infections     hematopoietic stem cell transplantation     risk stratification system    

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Superiority of allogeneic hematopoietic stem cell transplantation to nilotinib and dasatinib for adult

Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 304-311 doi: 10.1007/s11684-015-0400-4

Abstract: disease that progressed to accelerated phase following imatinib therapy, allogeneic hematopoietic stem celltransplantation (allo-HSCT) is the only curative therapy.

Keywords： chronic myeloid leukemia     imatinib     dasatinib     nilotinib     allogeneic hematopoietic stem cell transplantation    

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Quantitative proteomics revealed extensive microenvironmental changes after stem cell transplantation

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 429-441 doi: 10.1007/s11684-021-0842-9

Abstract: The local microenvironment is essential to stem cell-based therapy for ischemic stroke, and spatiotemporalinvestigate the microenvironmental changes in the subacute and chronic phases of ischemic stroke after stem celltransplantation.

Keywords： ischemic stroke     microenvironment     induced pluripotent stem cells (iPSCs)     positron emission tomography (PET)     quantitative proteomics    

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Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 522-526 doi: 10.1007/s11684-016-0485-4

Abstract:

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with continuous or recurrent symptoms. A 42-year-old male patient with intermittent diarrhea accompanied by bloody mucopurulent stools was admitted to our hospital. The diagnosis of UC was confirmed by a combination of laboratory examination, colonoscopy, and histological assay. The patient developed herpes zoster in the hospital, which challenged traditional treatments. Therefore, we performed an autologous bone marrow cells to modulate the immune system with his permission. Autologous bone marrow mononuclear cells were collected and injected locally into the bowel mucosa, and subsequently injected systemically through a peripheral vein. After the patient underwent auto bone marrow mononuclear cells transplantations twice, the patient’s symptoms were alleviated. Furthermore, he recovered from hematochezia, and his hypersensitive C reactive protein decreased. Colonoscopy results showed reduced lesions and decreased areas with bleeding and edema in the sigmoid colon and rectum. No recurrence occurred in the subsequent two years, but long-time monitoring is still necessary for the prophylaxis of colorectal cancer.

Keywords： autograft     bone marrow stem cells     ulcerative colitis     cell therapy    

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Liver cell therapies: cellular sources and grafting strategies

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 432-457 doi: 10.1007/s11684-023-1002-1

Abstract: The primary cell types in the liver are two parenchymal cell populations, hepatocytes and cholangiocytestypes comprising stellate cells, endothelia and various hemopoietic cell populations.Meanwhile breakthroughs in strategies for cell transplantation are enabling a future in which there candiseases, offering potential solutions to the chronic shortage of livers and alternatives to liver transplantationtransplantation that now include grafting strategies.

Keywords： liver regeneration     hepatocytes     cholangiocytes     stem cells     organoids     regulatory mechanisms     transplantation    

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Advancement of human leukocyte antigen-partially matched related hematopoietic stem cell transplantation

Xiaodong Mo, Xiaojun Huang

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 306-315 doi: 10.1007/s11684-013-0279-x

Abstract:

Allogeneic hematopoietic stem cell transplantation (HSCT) is one of the most effective options forSeveral protocols (with or without ex vivo T-cell depletion (TCD)) have been established worldwideassociated with prolonged immune deficiencies, increased risks of infectious complications, and high transplantation-related

Keywords： partially matched related donor     hematopoietic stem cell transplantation     allogeneic    

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Autologous peripheral hematopoietic stem-cell transplantation in a patient with refractory pemphigus

SUN Ledong, SUN Jing, ZENG Kang, MENG Fanyi, DIAO Youtao, XU Dan, HUANG Liang, ZHAO Jie, Liu Qifa

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 191-194 doi: 10.1007/s11684-008-0036-8

Abstract: The aim of this study is to explore the effectiveness of autologous peripheral hematopoietic stem-celltransplantation in the treatment of refractory pemphigus.Autologous peripheral hematopoietic stem cell transplantation was followed by reconstitution of the immuneThe glucocorticoid was withdrawn immediately after transplantation.The patient’s response suggests that autologous peripheral hematopoietic stem cell transplantation may

Keywords： serological activity     leukapheresis     peripheral hematopoietic     cyclophosphamide     resistance    

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Second unmanipulated allogeneic transplantation could be used as a salvage option for patients with relapsed

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 728-739 doi: 10.1007/s11684-021-0833-x

Abstract: Relapse is the main problem after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

Keywords： second hematopoietic stem cell transplantation     acute leukemia     relapse     chemotherapy     modified donor    

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donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem celltransplantation

Meng Lv, Yingjun Chang, Xiaojun Huang

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 45-56 doi: 10.1007/s11684-017-0595-7

Abstract: Human leukocyte antigen (HLA)-matched donors for hematopoietic stem cell transplantation (HSCT) have

Keywords： haploidentical hematopoietic stem cell transplantation     conditioning     graft-versus-host disease     relapse    

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Advances in Autologous Bone Marrow Stem Cell Transplantation

Li Lianda,Wu Limao,Liu Hong,Ning Keyong,Li Yikui

Strategic Study of CAE 2004, Volume 6, Issue 8,   Pages 1-4

Abstract:

Cellular transplantation is emerging as a potential treatment.Autologous cell transplantation for the treatment of damaged organs is becoming an increasingly promisingThis review summarizes the field of cell transplantation over the past decade, discusses areas of controversytransplantation to fully reach its clinical potential.It also discusses the current status of autologous bone marrow stem cell transplantation with emphases

Keywords： bone marrow stem cells     autologous transplantation     bone marrow mobilizer    

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Disease Risk Comorbidity Index for Patients Receiving Haploidentical Allogeneic Hematopoietic Transplantation Article

Xiao-Dong Mo, Xiao-Hui Zhang, Lan-Ping Xu, Yu Wang, Chen-Hua Yan, Huan Chen, Yu-Hong Chen, Wei Han, Feng-Rong Wang, Jing-Zhi Wang, Kai-Yan Liu, Xiao-Jun Huang

Engineering 2021, Volume 7, Issue 2,   Pages 162-169 doi: 10.1016/j.eng.2020.12.005

Abstract: develop a disease risk comorbidity index (DRCI) based on disease risk index (DRI) and Hematopoietic CellTransplantation-Specific Comorbidity Index (HCT-CI) in patients receiving haploidentical hematopoieticstem cell transplantation (haplo-HSCT).The multivariable model identified two independent predictors of DFS: DRI and HCT-CI before transplantation

Keywords： Disease risk index     Disease risk comorbidity index     Hematopoietic cell transplantation     comorbidity index     Hematopoietic stem cell transplantation     Haploidentical    

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Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 1-7 doi: 10.1007/s11684-010-0105-7

Abstract:

Partial liver transplantation, including reduced-size liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques becauseReduced-size liver transplantation is based on Couinaud’s anatomical classification, benefitingThe first and most important issue involving living donor liver transplantation is donor safety.transplantation, which employ piggyback techniques, are good alternatives.

Keywords： partial liver transplantation     reduced-size liver transplantation     split liver transplantation     living donorliver transplantation    

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Successful kidney transplantation in highly sensitized patients

Weijie ZHANG, Dong CHEN, Zhishui CHEN, Fanjun ZENG, Changsheng MING, Zhengbin LIN, Ping ZHOU, Gang CHEN, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 80-85 doi: 10.1007/s11684-011-0115-0

Abstract: survival rates; hence, sensitization is a significant barrier to both access to and the success of organ transplantationThis study reports our experience in kidney transplantation in highly sensitized patients.desensitization using PP/IVIG with or without rituximab increases the likelihood of successful live-donor kidney transplantation

Keywords： Kidney transplantation     desensitization    

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Title Author Date Type Operation

Lung transplantation for bronchiolitis obliterans syndrome after allogenic hematopoietic stem cell transplantation

Fei Gao, Jingyu Chen, Dong Wei, Bo Wu, Min Zhou

Journal Article

Fludarabine and intravenous busulfan conditioning with post-transplantation cyclophosphamide for allogeneicperipheral stem cell transplantation for adult patients with lymphoid malignancies: a prospective single-arm

Ling Wang, Lining Wang, Xing Fan, Wei Tang, Jiong Hu

Journal Article

Risk stratification system for skin and soft tissue infections after allogeneic hematopoietic stem celltransplantation: PAH risk score

Journal Article

Superiority of allogeneic hematopoietic stem cell transplantation to nilotinib and dasatinib for adult

Lanping Xu,Huanling Zhu,Jianda Hu,Depei Wu,Hao Jiang,Qian Jiang,Xiaojun Huang

Journal Article

Quantitative proteomics revealed extensive microenvironmental changes after stem cell transplantation

Journal Article

Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Journal Article

Liver cell therapies: cellular sources and grafting strategies

Journal Article

Advancement of human leukocyte antigen-partially matched related hematopoietic stem cell transplantation

Xiaodong Mo, Xiaojun Huang

Journal Article

Autologous peripheral hematopoietic stem-cell transplantation in a patient with refractory pemphigus

SUN Ledong, SUN Jing, ZENG Kang, MENG Fanyi, DIAO Youtao, XU Dan, HUANG Liang, ZHAO Jie, Liu Qifa

Journal Article

Second unmanipulated allogeneic transplantation could be used as a salvage option for patients with relapsed

Journal Article

donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem celltransplantation

Meng Lv, Yingjun Chang, Xiaojun Huang

Journal Article

Advances in Autologous Bone Marrow Stem Cell Transplantation

Li Lianda,Wu Limao,Liu Hong,Ning Keyong,Li Yikui

Journal Article

Disease Risk Comorbidity Index for Patients Receiving Haploidentical Allogeneic Hematopoietic Transplantation

Xiao-Dong Mo, Xiao-Hui Zhang, Lan-Ping Xu, Yu Wang, Chen-Hua Yan, Huan Chen, Yu-Hong Chen, Wei Han, Feng-Rong Wang, Jing-Zhi Wang, Kai-Yan Liu, Xiao-Jun Huang

Journal Article

Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Journal Article

Successful kidney transplantation in highly sensitized patients

Weijie ZHANG, Dong CHEN, Zhishui CHEN, Fanjun ZENG, Changsheng MING, Zhengbin LIN, Ping ZHOU, Gang CHEN, Xiaoping CHEN

Journal Article